Organosilicon Chemistry From Molecules to Materials

Contemporary organosilicon chemistry

Editorial for the Thematic Series on Contemporary Organosilicon Chemistry.

Chemistry across scales: from molecules to cells.

Many important biological functions are strongly dependent on specific chemical interactions. Modelling how the physicochemical molecular details emerge at much larger scales is an active area of research, currently pursued with a variety of methods. We describe a series of theoretical and computational approaches that aim to derive bottom-up descriptions that capture the specificity that ensue...

Polyoxometalates: from inorganic chemistry to materials science.

Polyoxometalates have been traditionally the subject of study of molecular inorganic chemistry. Yet, these polynuclear molecules, reminiscent of oxide clusters, present a wide range of structures and with them ideal frameworks for the deployment of a plethora of useful magnetic, electroionic, catalytic, bioactive and photochemical properties. With this in mind, a new trend towards the applicati...

Synthesis and cellular profiling of diverse organosilicon small molecules.

Small-molecule synthesis coupled with cellular profiling using multidimensional screening has been used to assess the role of stereochemical and skeletal variation on assay outcomes, albeit within a limited structure space.1 Here, we provide an extension of this approach as a framework to assess the role of a main-group element on assay outcomes. We considered that incorporating, for example, b...

Magnetism: Molecules to Materials IV